Active ingredient
Aflibercept
9 finished FDA listings contain Aflibercept as their only active ingredient.
FDA NDC Directory
- Ingredient names as written by FDA
- AFLIBERCEPT, AFLIBERCEPT-JBVF, AFLIBERCEPT-MRBB, AFLIBERCEPT-YSZY
- Dosage forms
- Injection, Solution, Solution, Concentrate
- Routes
- Intravenous, Intravitreal
- Manufacturers / labelers
- 6
- Strengths listed
- 100 mg/4ml · 2 mg/.05ml · 200 mg/8ml · 40 mg/ml · 8 mg/.07ml
- Brand names in FDA listings
- Ahzantive, Eylea, Eylea Hd, Pavblu, Yesafili, Zaltrap
RxNorm (National Library of Medicine)
Ingredient concept RxCUI 1232150
Drugs@FDA applications
Linked only where the FDA listing’s application number matches Drugs@FDA exactly. A listing in the NDC Directory does not by itself mean FDA approval.
| Application | Sponsor | Original approval | Listings |
|---|---|---|---|
| BLA 125387 | REGENERON PHARMACEUTICALS | 2011-11-18 | 1 |
| BLA 125418 | SANOFI AVENTIS US | 2012-08-03 | 2 |
| BLA 761355 | REGENERON PHARMACEUTICALS | 2023-08-18 | 2 |
| BLA 761274 | BIOCON BIOLOGICS INC | 2024-05-20 | 1 |
| BLA 761378 | FORMYCON AG | 2024-06-28 | 1 |
| BLA 761298 | AMGEN INC | 2024-08-23 | 2 |
Official labeling on DailyMed
- EYLEA (AFLIBERCEPT) INJECTION, SOLUTION [REGENERON PHARMACEUTICALS, INC.] · version 41 · 2026-07-23
- PAVBLU (AFLIBERCEPT-AYYH) INJECTION, SOLUTION [AMGEN, INC] · version 9 · 2026-05-13
- EYLEA HD (AFLIBERCEPT) INJECTION, SOLUTION [REGENERON PHARMACEUTICALS, INC] · version 12 · 2026-04-10
- AHZANTIVE (AFLIBERCEPT-MRBB) INJECTION, SOLUTION [VALORUM BIOLOGICS, LLC] · version 7 · 2025-11-24
- ZALTRAP (ZIV-AFLIBERCEPT) SOLUTION, CONCENTRATE [SANOFI-AVENTIS U.S. LLC] · version 28 · 2025-11-17
Sources: FDA NDC Directory (2026-09-29), RxNorm, Drugs@FDA, DailyMed. Each source’s facts are shown separately as published.