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Active ingredient

Diphenhydramine

743 finished FDA listings contain Diphenhydramine as their only active ingredient; 381 combination products also contain it.

FDA NDC Directory

Ingredient names as written by FDA
DIPHENHYDRAMINE, DIPHENHYDRAMINE CITRATE, DIPHENHYDRAMINE HCL, DIPHENHYDRAMINE HYDROCHLORIDE
Dosage forms
Bar, Chewable, Capsule, Capsule, Gelatin Coated, Capsule, Liquid Filled, Chewable Gel, Gel, Injection, Injection, Solution, Liquid, Solution, Spray, Syrup, Tablet, Tablet, Chewable, Tablet, Coated, Tablet, Film Coated
Routes
Intramuscular, Intravenous, Oral, Topical
Manufacturers / labelers
266
Strengths listed
.4 g/20g · .51 g/25.5g · 1.14 g/57g · 12.5 mg/1 · 12.5 mg/10ml · 12.5 mg/15ml · 12.5 mg/5ml · 2 g/100g · 2 g/100ml · 2 mg/100ml · 20 mg/g · 20 mg/ml · 20.3 g/l · 25 mg/1 · 25 mg/10ml · 25 mg/25mg · 25 mg/5ml · 50 mg/1 · 50 mg/20ml · 50 mg/21 · 50 mg/30ml · 50 mg/3ml · 50 mg/g · 50 mg/ml
Brand names in FDA listings (first 80 of 255, A–Z)
A Health Itch Relief Gel, Adult Allergy Relief, Adult Allergy Relief Dye Free, Adwe Dye-Free Childrens Allergy, After Bite Outdoor, After Bite Xtra, Allergies My Child Needs Help With, Allergy, Allergy 36ct, Caseys 4good, Allergy Antihistamine, Allergy Childrens, Allergy Childrens Allergy, Allergy Medicine, Allergy Relief, Allergy Relief 25 Mg, Allergy Relief Caplet, Allergy Relief Childrens, Allergy Relief Complete, Allergy Relief Diphenhydramine Hcl, Allergy Relief Diphenhydramine Hcl 25mg Softgel, Allergy Relief Diphenhydramine Hcl 50 Mg, Allergy Relief Dye Free, Allergy Relief Dye-Free, Allergy Relief Dye-Free Softgel, Allergy Relief Extra Strength, Allergy Relief Mini Softgels, Allergy Relief, 24-7 Life By 7-Eleven, Allergy Relief, 24-7 Lift By 7-Eleven, Allergy, Circle K, Allergy, Lil Drug Store, Antihistamine, Axiv - Vrozzz, Axiv Allergy, Axiv Allergy Relief, Bactimicina Childrens Allergy, Banophen, Basic Care Allergy Relief, Basic Care Childrens Allergy Relief, Basic Care Nighttime Sleep Aid, Benadryl, Benadryl Allergy, Benadryl Allergy Extra Strength, Benadryl Allergy Extra Strength Liqui-Gels, Benadryl Allergy Liqui-Gels, Benadryl Allergy Ultratab, Benadryl Extra Strength Itch Stopping, Benadryl Ultratabs, Berkley And Jensen Allergy Relief, Berkley And Jensen Sleep Aid, Best Choice Childrens Allergy Relief Bubblegum Flavor, Best Choice Itch Stopping, Betr Sleep Aid, Cabinet Allergy Relief Refill Diphenhydramine Hci, Calmco Allergy Relief, Calmco Sleep Aid, Calmco Sleep Aid Gummy Bite, Careall Allergy Relief, Careall Diphenhydramine, Careone Allergy Relief, Careone Childrens Allergy Relief, Careone Nighttime Sleep Aid, Children Allergy Relief Bubblegum Flavor, Children Allergy Relief Dye Free Cherry, Childrens Allergy, Childrens Allergy Dye Free Wal Dryl, Childrens Allergy Relief, Childrens Allergy Relief Dye Free, Childrens Allergy Relief Dye-Free, Childrens Benadryl Allergy, Childrens Benadryl Chewables, Childrens Benadryl Dye-Free Allergy, Childrens Chewable Allergy Relief, Childrens Dye Free Allergy, Childrens Dye Free Allergy Relief, Circle K Allergy Antihistamine, Complete Allergy Medicine, Cvs Diphenhydramine Hydrochloride, Cvs Dye-Free Childrens Allergy, Cvs Health Childrens Allergy Relief, Cvs Health Nighttime Sleep Aid

RxNorm (National Library of Medicine)

Ingredient concept RxCUI 3498

Drugs@FDA applications

Linked only where the FDA listing’s application number matches Drugs@FDA exactly. A listing in the NDC Directory does not by itself mean FDA approval.

ApplicationSponsorOriginal approvalListings
ANDA 080817WEST-WARD PHARMS INT1972-11-2711
ANDA 087513PHARM ASSOC1982-02-104
ANDA 040466APP PHARMS2002-05-286
ANDA 091526FRESENIUS KABI USA2013-03-262
ANDA 205723MICRO LABS2018-08-226
ANDA 218448GLAND2024-03-202
ANDA 205336AVET LIFESCIENCES2025-06-244
ANDA 219845MICRO LABS2025-08-221
ANDA 205337AVET LIFESCIENCES2025-11-141
ANDA 219470ANNORA PHARMA2026-06-172

Official labeling on DailyMed

Showing the 12 most recent of 702 labels.

Sources: FDA NDC Directory (2026-09-29), RxNorm, Drugs@FDA, DailyMed. Each source’s facts are shown separately as published.