Active ingredient
Oxymetazoline
219 finished FDA listings contain Oxymetazoline as their only active ingredient.
FDA NDC Directory
- Ingredient names as written by FDA
- OXYMETAZOLINE, OXYMETAZOLINE HYDROCHLORIDE
- Dosage forms
- Aerosol, Spray, Cream, Liquid, Solution, Solution/ Drops, Spray, Spray, Metered
- Routes
- Nasal, Ophthalmic, Topical
- Manufacturers / labelers
- 95
- Strengths listed
- .0005 g/g · .0005 g/ml · .0005095 g/ml · .025 g/100ml · .05 g/100ml · .05 g/ml · .05 mg/1 · .05 mg/100ml · .05 mg/ml · .4 mg/ml · .5 g/100ml · .5 mg/ml · 1 g/100g · 1 mg/ml · 10 mg/g · 15 mg/30ml · 15.21 mg/30ml · 5 g/100ml · 50 mg/100ml · 50 mg/ml · 7.5 mg/15ml
- Brand names in FDA listings (first 80 of 149, A–Z)
- 12 Hour Nasal Decongestant Extra Moisturizing, 12 Hour Original Nasal Decongestant, Afrin, Afrin Allergy Sinus Nasal, Afrin No Drip Extra Moisturizing, Afrin No Drip Original Pump Mist, Afrin No Drip Severe Congestion, Afrin No-Drip Allergy Sinus, Afrin Nodrip Allergy Sinus Night, Afrin Original, Afrin Original Nasal, Afrin Original Pump Mist, Afrin Severe Congestion, Anefrin Nasal Original, Avon Hexashield Congestion Relief Original, Axiv Sinus Overnight, Axiv Sinus Severe Ultra Fine Mist, Basic Care Nasal, Basic Care No Drip Nasal, Berkley And Jensen Nasal, Best Choice, Best Choice Maximum Strength, Best Choice No Drip, Best Choice Ultra Fine Mist, Care One Nasal Original, Careone Severe Congestion Nasal, Children Afrin Extra Moisturizing Stuffy Nose Pump Mist Stuffy Nose Pump Mist, Children Afrin No Drip Extra Moisturizing Stuffy Nose Pump Mist Stuffy Nose Pump Mist, Circle K Congestion Relief, Congestion Relief Lil Drug Store Products, Cvs Health, Cvs Health No Drip, Cvs Health Sinus, Cvs Health Sinus Relief, Cvs Health Ultra Fine Mist, Cvs Moisturizing Nasal, Cvs Original Nasal Mist, Cvs Severe Nasal Congestion Relief Clear And Cool, Dg Health Nasal, Dg Health Nasal Original, Dg Health Sinus Severe, Discount Drug Mart Extra Moisturizing, Discount Drug Mart Maximum Strength Nasal, Discount Drug Mart Original Nasal, Discount Drug Mart Severe Congestion Nasal, Discount Drug Mart Severe Nasal, Dristan 12 Hr, Equaline Nasal, Equate, Equate Nasal, Equate Nasal Original, Exchange Select Nasal, Extra Moisturizing Nasal Pump Mist Anti Drip, Family Care Nasal Relief, Family Dollar, Family Dollar Ultra Fine Mist Sinus Relief, Family Wellness Oxymetazoline, Family Wellness Oxymetazoline No Drip, Family Wellness Oxymetazoline Sinus Severe, Foster And Thrive Nasal, Giltuss Severe Sinus, Good Neighbor No Drip Nasal Mist Extra Moisturizing, Good Neighbor Pharmacy Nasal, Good Neighbor Pharmacy No Drip Nasal Mist, Good Sense Nasal, Kroger No Drip, Kroger No Drip Nasal Mist Severe Congestion, Leader Nasal Decongestant, Leader No Drip, Major Nasal Decongestant, Marc Glassman Maximum Strength, Maximum Strength Nasal Decongestant, Meijer Original, Mucinex Childrens Stuffy Nose, Mucinex Sinus Max Clear And Cool Severe Congestion, Mucinex Sinus Max Sinus Pressure Severe Congestion, Mucinex Sinus-Max Severe Congestion Relief Sinus And Allergy, Mucinex Sinus-Max Severe Nasal Congestion Relief Clear And Cool Nasal, Nasal, Nasal 12 Hour
RxNorm (National Library of Medicine)
Ingredient concept RxCUI 7812
Drugs@FDA applications
Linked only where the FDA listing’s application number matches Drugs@FDA exactly. A listing in the NDC Directory does not by itself mean FDA approval.
| Application | Sponsor | Original approval | Listings |
|---|---|---|---|
| NDA 208552 | MAYNE PHARMA | 2017-01-18 | 3 |
| NDA 212520 | RVL PHARMS | 2020-07-08 | 1 |
| ANDA 213584 | SUN PHARMA CANADA | 2021-10-04 | 1 |
Official labeling on DailyMed
- NOSTRILLA (OXYMETAZOLINE HYDROCHLORIDE) SPRAY, METERED [INSIGHT PHARMACEUTICALS LLC] · version 8 · 2026-09-10
- NASAL (OXYMETAZOLINE HYDROCHLORIDE) SPRAY, METERED [RITE AID CORPORATION] · version 4 · 2026-09-07
- EQUATE NASAL (OXYMETAZOLINE HCL) SPRAY, METERED [SIXARP, LLC] · version 1 · 2026-09-07
- NO MORE NOSEBLEED (OXYMETAZOLINE HYDROCHLORIDE) LIQUID [DR. FRIEDMAN'S NO MORE NOSEBLEED KIT INC.] · version 8 · 2026-09-07
- ULTRA FINE MIST SINUS RELIEF (OXYMETAZOLINE HYDROCHLORIDE) SPRAY [DOLGENCORP, INC.] · version 7 · 2026-09-04
- KROGER NO DRIP (ALLERGY SINUS) SPRAY [KROGER COMPANY] · version 8 · 2026-09-03
- KROGER NO DRIP NASAL MIST SEVERE CONGESTION (OXYMETAZOLINE HYDROCHLORIDE) SPRAY [KROGER COMPANY] · version 4 · 2026-09-03
- UPNEEQ (OXYMETAZOLINE HYDROCHLORIDE OPHTHALMIC) SOLUTION/ DROPS [RVL PHARMACEUTICALS, INC.] · version 30 · 2026-09-02
- AFRIN ORIGINAL NASAL (OXYMETAZOLINE HYDROCHLORIDE) SPRAY [JC WORLD BELL WHOLESALE CO., INC.] · version 2 · 2026-09-02
- ZICAM INTENSE SINUS RELIEF (OXYMETAZOLINE HYDROCHLORIDE) SPRAY [CHURCH & DWIGHT CO., INC.] · version 4 · 2026-09-02
- VICKS SINEX SEVERE CONGESTION MOISTURIZING ULTRA FINE MIST (OXYMETAZOLINE HYDROCHLORIDE) SPRAY [PROCTER & GAMBLE MANUFACTURING GMBH] · version 4 · 2026-08-25
- NASAL (OXYMETAZOLINE HYDROCHLORIDE) SPRAY [AMAZON.COM SERVICES LLC] · version 2 · 2026-08-21
Showing the 12 most recent of 204 labels.
Sources: FDA NDC Directory (2026-09-29), RxNorm, Drugs@FDA, DailyMed. Each source’s facts are shown separately as published.